Osteoarthritis (OA), the most
common cause of degenerative
joint disease (DJD) in dogs, is a
chronic, progressive, noninfectious
joint disorder that leads to degeneration of articular cartilage and
proliferative changes. Damage to
articular cartilage may result from
abnormal stresses that disrupt the
normal articular surface, in turn
leading to joint instability. Consequently, the normal wear pattern
as well as the mauzo of articular
matrix are accelerated.1 This process
is also accelerated kwa cytokines and
prostaglandins released kwa synovial
cells into the joint. As a result, the
joint capsule thickens...